Weny J. A. Musa, Nurhayati Bialangi, Ahmad Kadir Kilo, C.J. Lamangantjo, Boima Situmeang, Agus Malik Ibrahim
Caesalpinia bonducella, known as ‘tombili’ belongs to the family of Fabaceae. Tombili has been empirically used as traditional medicine. In a previous study, phytochemical screening showed that tombili seed contained alkaloid, flavonoid, terpenoid, and tannin compounds. This research aimed to isolate an antioxidant compound from tombili seed extract. Fractionated using n-hexane, ethyl acetate, and methanol as a solvent. All fractions were tested for their antioxidant potential. The ethyl acetate fraction gave a better antioxidant potential (IC50 86.153±4.22 ppm) than it has purified. Characterization of an isolated compound using various spectroscopies data, including UV, FTIR, 1D-NMR, 2D-NMR, and LCMS/MS. The structure of the isolated compound was suggested as 7-(β-D-Glucopyranosyloxy) 5-hydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one (homoplantaginin). The IC50 value of the isolated compound was 40.53 ±3.13 ppm, indicating the isolated compound has potent antioxidant activity. © 2022, Rasayan Journal of Chemistry, c/o Dr. Pratima Sharma. All rights reserved.
Department of Chemistry, Faculty of Mathematics and Natural Sain, Gorontalo State University, Gorontalo, 96128, Indonesia; Department of Biology, Faculty of Mathematics and Natural Sains, Gorontalo State University, Gorontalo, 96128, Indonesia; Department of Chemistry, Sekolah Tinggi Analis Kimia Cilegon, Banten, 42161, Indonesia
Research at a Glance
Register to unlock
Topics & SDG Alignment
Register to unlock
Collaboration
Register to unlock
Author Profile (Selected)
Register to unlock
References Overview
Register to unlock
Journal & Source
Register to unlock
Metadata & Integrity
Register to unlock